RT Journal Article T1 The Evolving Microbiome from Pregnancy to Early Infancy: A Comprehensive Review A1 Mesa, María Dolores A1 Loureiro, Begoña A1 Iglesia, Iris A1 Fernandez Gonzalez, Sergi A1 Llurba Olivé, Elisa A1 García Algar, Oscar A1 Solana, María José A1 Cabero Perez, Mª Jesús A1 Sainz, Talia A1 Martinez, Leopoldo A1 Escuder-Vieco, Diana A1 Parra-Llorca, Anna A1 Sánchez-Campillo, María A1 Rodriguez Martinez, Gerardo A1 Gómez Roig, Dolores A1 Perez Gruz, Myriam A1 Andreu-Fernández, Vicente A1 Clotet, Jordi A1 Sailer, Sebastian A1 Iglesias-Platas, Isabel A1 López-Herce, Jesús A1 Aras, Rosa A1 Pallás-Alonso, Carmen A1 Saenz de Pipaon, Miguel A1 Vento, Máximo A1 Gormaz, María A1 Larqué Daza, Elvira A1 Calvo, Cristina A1 Cabañas, Fernando K1 Microbiome K1 Pregnancy K1 Fetus K1 Placenta K1 Newborn K1 Infancy K1 Critical illness K1 Sepsis K1 Allergy K1 Microbiota K1 Embarazo K1 Feto K1 Placenta K1 Recién nacido K1 Lactante K1 Enfermedad crítica K1 Alergia e inmunología AB Pregnancy induces a number of immunological, hormonal, and metabolic changes that are necessary for the mother to adapt her body to this new physiological situation. The microbiome of the mother, the placenta and the fetus influence the fetus growth and undoubtedly plays a major role in the adequate development of the newborn infant. Hence, the microbiome modulates the inflammatory mechanisms related to physiological and pathological processes that are involved in the perinatal progress through different mechanisms. The present review summarizes the actual knowledge related to physiological changes in the microbiota occurring in the mother, the fetus, and the child, both during neonatal period and beyond. In addition, we approach some specific pathological situations during the perinatal periods, as well as the influence of the type of delivery and feeding. PB MDPI YR 2020 FD 2020-01-02 LK http://hdl.handle.net/10668/3694 UL http://hdl.handle.net/10668/3694 LA en NO Mesa MD, Loureiro B, Iglesia I, Fernandez Gonzalez S, Llurba Olivé E, García Algar O, et al. The Evolving Microbiome from Pregnancy to Early Infancy: A Comprehensive Review. Nutrients. 2020 Jan 2;12(1):133 DS RISalud RD Apr 18, 2025