RT Journal Article T1 The Role of Positive Psychological Factors in the Association between Pain Intensity and Pain Interference in Individuals with Chronic Musculoskeletal Pain: A Cross-Sectional Study A1 Martinez-Calderon, Javier A1 Flores-Cortes, Mar A1 Clavero-Cano, Susana A1 Morales-Asencio, Jose Miguel A1 Jensen, Mark P. A1 Rondon-Ramos, Antonio A1 Diaz-Cerrillo, Juan Luis A1 Ariza-Hurtado, Gina Rocío A1 Luque-Suarez, Alejandro K1 Chronic pain K1 Cognition K1 Cross-sectional studies K1 Musculoskeletal pain K1 Optimism K1 Pain K1 Self-efficacy K1 Dolor crónico K1 Cognición K1 Estudios transversales K1 Dolor musculoesquelético K1 Optimismo K1 Dolor K1 Autoeficacia AB This study aimed to test the cross-sectional mediating and moderating role that positive psychological factors play in the association between pain intensity and pain interference in individuals with chronic musculoskeletal pain. A descriptive cross-sectional study using mediation analyses was conducted, including 186 individuals with chronic musculoskeletal pain. We conducted cross-sectional mediation and moderation analyses to determine whether the positive psychological factors mediated or moderated the association between pain intensity and pain interference. Pain acceptance, pain self-efficacy, and optimism were all significantly and weakly related to pain interference when controlling for pain intensity. Pain self-efficacy and pain acceptance partially mediated the association between pain intensity and pain interference. On the other hand, the multiple mediation model did not show significant effects. The three positive psychological factors were not found to significantly moderate the association between pain intensity and pain interference. The findings suggest that in chronic musculoskeletal pain patients, the treatments may focus on [i] what they are capable of doing to manage the pain (i.e., pain self-efficacy) and [ii] being better able to accept the pain as pain waxes and wanes might be also particularly helpful. However, these results must be tested in longitudinal studies before drawing any causal conclusion. PB MDPI YR 2020 FD 2020-10-12 LK http://hdl.handle.net/10668/3845 UL http://hdl.handle.net/10668/3845 LA en NO Martinez-Calderon J, Flores-Cortes M, Clavero-Cano S, Morales-Asencio JM, Jensen MP, Rondon-Ramos A, et al. The Role of Positive Psychological Factors in the Association between Pain Intensity and Pain Interference in Individuals with Chronic Musculoskeletal Pain: A Cross-Sectional Study. J Clin Med. 2020 Oct 12;9(10):3252 DS RISalud RD Apr 17, 2025