TY - JOUR AU - OƱate, Maritza AU - Catenaccio, Alejandra AU - Salvadores, Natalia AU - Saquel, Cristian AU - Martinez, Alexis AU - Moreno-Gonzalez, Ines AU - Gamez, Nazaret AU - Soto, Paulina AU - Soto, Claudio AU - Hetz, Claudio AU - Court, Felipe A PY - 2019 DO - 10.1038/s41418-019-0408-4 UR - http://hdl.handle.net/10668/14594 T2 - Cell death and differentiation AB - Parkinson's disease (PD) is the second most common neurodegenerative condition, characterized by motor impairment due to the progressive degeneration of dopaminergic neurons in the substantia nigra and depletion of dopamine release in the striatum.... LA - en KW - Animals KW - Axons KW - Biomarkers KW - Disease Models, Animal KW - Dopaminergic Neurons KW - Humans KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Motor Activity KW - Necroptosis KW - Nerve Degeneration KW - Neurites KW - Oxidopamine KW - Parkinson Disease KW - Phosphorylation KW - Protein Kinases KW - Receptor-Interacting Protein Serine-Threonine Kinases KW - Substantia Nigra TI - The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease. TY - research article VL - 27 ER -