RT Journal Article
T1 Replacing red meat and processed red meat for white meat, fish, legumes or eggs is associated with lower risk of incidence of metabolic syndrome.
A1 Becerra-Tomás, Nerea
A1 Babio, Nancy
A1 Martínez-González, Miguel Ángel
A1 Corella, Dolores
A1 Estruch, Ramon
A1 Ros, Emilio
A1 Fitó, Montserrat
A1 Serra-Majem, Lluís
A1 Salaverria, Itziar
A1 Lamuela-Raventós, Rosa M
A1 Lapetra, José
A1 Gómez-Gracia, Enrique
A1 Fiol, Miguel
A1 Toledo, Estefanía
A1 Sorlí, José V
A1 Pedret-Llaberia, Maria Roser
A1 Salas-Salvadó, Jordi
K1 Metabolic syndrome
K1 PREDIMED-study
K1 Processed red meat
K1 Red meat
K1 Total meat
AB Few studies have assessed the association between consumption of red meat (RM) and processed red meats (PRM) and the incidence of metabolic syndrome (MetS) and results have been inconsistent. We investigated associations between total consumption of meat and its subtypes and incident MetS and estimated the effect of substituting RM or PRM for alternative protein-rich foods. We analyzed 1868 participants (55-80 years-old) recruited into the PREDIMED study who had no MetS at baseline and were followed for a median of 3.2 years. MetS was defined using updated harmonized criteria. Anthropometric variables, dietary habits, and blood biochemistry were determined at baseline and yearly thereafter. Multivariable-adjusted hazard ratios (HRs) of MetS were estimated for the two upper tertiles (versus the lowest one) of mean consumption of meat and its subtypes during the follow-up as exposure. Comparing the highest vs the lowest tertile of consumption, we observed an increased risk of MetS incidence, with HRs of 1.23 (95% confidence interval [CI]: 1.03-1.45) and 1.46 (CI: 1.22-1.74) for total meat and pooled RM and PRM, respectively. Compared with participants in the lowest tertile, those in the highest tertile of poultry and rabbit consumption had a lower risk of MetS incidence. The risk of MetS was lower when one-serving/day of RM or PRM was replaced by legumes, poultry and rabbit, fish or eggs. RM and PRM consumption was associated with higher risk of MetS. Replacing RM or PRM with other protein-rich foods related to a lower risk of MetS and should, therefore, be encouraged. This trial was registered at controlled-trials.com as ISRCTN35739639.
YR 2016
FD 2016-03-31
LK http://hdl.handle.net/10668/9999
UL http://hdl.handle.net/10668/9999
LA en
DS RISalud
RD Apr 11, 2025