TY - JOUR AU - Brown, Emmeline E AU - Blauwendraat, Cornelis AU - Trinh, Joanne AU - Rizig, Mie AU - Nalls, Mike A AU - Leveille, Etienne AU - Ruskey, Jennifer A AU - Jonvik, Hallgeir AU - Tan, Manuela M X AU - Bandres-Ciga, Sara AU - Hassin-Baer, Sharon AU - Brockmann, Kathrin AU - Infante, Jon AU - Tolosa, Eduardo AU - Ezquerra, Mario AU - Ben Romdhan, Sawssan AU - Benmahdjoub, Mustapha AU - Arezki, Mohamed AU - Mhiri, Chokri AU - Hardy, John AU - Singleton, Andrew B AU - Alcalay, Roy N AU - Gasser, Thomas AU - Grosset, Donald G AU - Williams, Nigel M AU - Pittman, Alan AU - Gan-Or, Ziv AU - Fernandez-Santiago, Ruben AU - Brice, Alexis AU - Lesage, Suzanne AU - Farrer, Matthew AU - Wood, Nicholas AU - Morris, Huw R PY - 2020 DO - 10.1016/j.neurobiolaging.2020.07.002 UR - http://hdl.handle.net/10668/16190 T2 - Neurobiology of aging AB - The LRRK2 gene has rare (p.G2019S) and common risk variants for Parkinson's disease (PD). DNM3 has previously been reported as a genetic modifier of the age at onset in PD patients carrying the LRRK2 p.G2019S mutation. We analyzed this effect in a new... LA - en PB - Elsevier Inc. KW - Genetic modifiers KW - Leucine-rich repeat kinase 2 KW - Parkinsonism KW - Parkinson’s disease KW - Age of Onset KW - Aged KW - Cohort Studies KW - Dynamin III KW - Epistasis, Genetic KW - Female KW - Genetic Association Studies KW - Genetic Predisposition to Disease KW - Genetic Variation KW - Humans KW - Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 KW - Linkage Disequilibrium KW - Male KW - Middle Aged KW - Parkinson Disease KW - R-SNARE Proteins KW - Risk TI - Analysis of DNM3 and VAMP4 as genetic modifiers of LRRK2 Parkinson's disease. TY - research article VL - 97 ER -