TY - JOUR AU - Yu, Edward AU - Ruiz-Canela, Miguel AU - Razquin, Cristina AU - Guasch-Ferré, Marta AU - Toledo, Estefania AU - Wang, Dong D AU - Papandreou, Christopher AU - Dennis, Courtney AU - Clish, Clary AU - Liang, Liming AU - Bullo, Monica AU - Corella, Dolores AU - Fitó, Montserrat AU - Gutiérrez-Bedmar, Mario AU - Lapetra, José AU - Estruch, Ramón AU - Ros, Emilio AU - Cofán, Montserrat AU - Arós, Fernando AU - Romaguera, Dora AU - Serra-Majem, Lluis AU - Sorlí, Jose V AU - Salas-Salvadó, Jordi AU - Hu, Frank B AU - Martínez-González, Miguel A PY - 2018 DO - 10.1111/dom.13514 UR - http://hdl.handle.net/10668/12873 T2 - Diabetes, obesity & metabolism AB - The associations between arginine-based metabolites and incident type 2 diabetes (T2D) are unknown. We employed a case-cohort design, nested within the PREDIMED trial, to examine six plasma metabolites (arginine, citrulline, ornithine, asymmetric... LA - en KW - cohort study KW - dietary intervention KW - insulin resistance KW - observational study KW - population study, type 2 diabetes KW - Aged KW - Aged, 80 and over KW - Arginine KW - Case-Control Studies KW - Citrulline KW - Cohort Studies KW - Diabetes Mellitus, Type 2 KW - Diet, Fat-Restricted KW - Diet, Mediterranean KW - Female KW - Humans KW - Incidence KW - Insulin Resistance KW - Male KW - Middle Aged KW - Ornithine KW - Risk Factors KW - omega-N-Methylarginine TI - Changes in arginine are inversely associated with type 2 diabetes: A case-cohort study in the PREDIMED trial. TY - research article VL - 21 ER -