TY  - JOUR
AU  - Buchrieser, Julian
AU  - Oliva-Martin, Maria Jose
AU  - Moore, Michael D
AU  - Long, Joshua C D
AU  - Cowley, Sally A
AU  - Perez-Simón, Jose Antonio
AU  - James, William
AU  - Venero, Jose Luis
PY  - 2018
DO  - 10.1038/s41419-018-1053-4
UR  - http://hdl.handle.net/10668/12990
T2  - Cell death & disease
AB  - In this study, we took advantage of human-induced pluripotent stem cells (hiPSC) and CRISPR/Cas9 technology to investigate the potential roles of RIPK1 in regulating hematopoiesis and macrophage differentiation, proinflammatory activation, and cell...
LA  - en
KW  - Adaptor Proteins, Vesicular Transport
KW  - Apoptosis
KW  - CRISPR-Cas Systems
KW  - Caspase 8
KW  - Cell Differentiation
KW  - Gene Editing
KW  - Gene Knockout Techniques
KW  - Hematopoiesis
KW  - Humans
KW  - Induced Pluripotent Stem Cells
KW  - Inflammation
KW  - Macrophages
KW  - Receptor-Interacting Protein Serine-Threonine Kinases
KW  - Toll-Like Receptor 3
KW  - Toll-Like Receptor 4
KW  - Tumor Necrosis Factor-alpha
TI  - RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation.
TY  - research article
VL  - 9
ER  -