TY  - JOUR
AU  - Roodveldt, Cintia
AU  - Labrador-Garrido, Adahir
AU  - Gonzalez-Rey, Elena
AU  - Lachaud, Christian C
AU  - Guilliams, Tim
AU  - Fernandez-Montesinos, Rafael
AU  - Benitez-Rondan, Alicia
AU  - Robledo, Gema
AU  - Hmadcha, Abdelkrim
AU  - Delgado, Mario
AU  - Dobson, Christopher M
AU  - Pozo, David
PY  - 2013
DO  - 10.1371/journal.pone.0079160
UR  - http://hdl.handle.net/10668/2279
T2  - PloS One
AB  - In recent years, it has become accepted that α-synuclein (αSyn) has a key role in the microglia-mediated neuroinflammation, which accompanies the development of Parkinson's disease and other related disorders, such as Dementia with Lewy Bodies and...
LA  - en
PB  - Public Library of Science
KW  - Microglial cells
KW  - Cytokines
KW  - Toll-Like Receptors
KW  - Fluorescence microscopy
KW  - Phagocytosis
KW  - Chemokines
KW  - Fluorescence imaging
KW  - Secretion
KW  - Receptores Toll-Like
KW  - Citocinas
KW  - Microscopía Fluorescente
KW  - Fagocitosis
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Ureohydrolases::Arginase
KW  - Medical Subject Headings::Organisms::Bacteria::Gram-Positive Bacteria::Bacillales::Bacillaceae::Bacillus::Bacillus subtilis
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intracellular Signaling Peptides and Proteins::Apoptosis Regulatory Proteins::Caspases::Caspases, Effector::Caspase 3
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Polarity
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression
KW  - Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immunity::Immunity, Innate
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Inbred Strains::Mice, Inbred C57BL
KW  - Medical Subject Headings::Anatomy::Cells::Neuroglia::Microglia
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Oxidoreductases Acting on CH-NH2 Group Donors::Amino Acid Oxidoreductases::Nitric Oxide Synthase::Nitric Oxide Synthase Type II
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Glycopeptides::Peptidoglycan
KW  - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleotides::Polynucleotides::Polyribonucleotides::Poly C::Poly I-C
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Pattern Recognition::Toll-Like Receptors
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nerve Tissue Proteins::Synucleins::alpha-Synuclein
KW  - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Quinolines::Aminoquinolines
TI  - Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation.
TY  - research article
ER  -