TY - JOUR AU - Rivera, Patricia AU - Bindila, Laura AU - Pastor, Antoni AU - Pérez-Martín, Margarita AU - Pavón, Francisco J AU - Serrano, Antonia AU - de la Torre, Rafael AU - Lutz, Beat AU - Rodríguez de Fonseca, Fernando AU - Suárez, Juan PY - 2015 DO - 10.3389/fncel.2015.00098 UR - http://hdl.handle.net/10668/2340 T2 - Frontiers in Cellular Neuroscience AB - Endocannabinoids participate in the control of neurogenesis, neural cell death and gliosis. The pharmacological effect of the fatty acid amide hydrolase (FAAH) inhibitor URB597, which limits the endocannabinoid degradation, was investigated in the... LA - en PB - Frontiers Media KW - URB597 KW - FAAH KW - Cannabinoids KW - Energy metabolism KW - Neurogenesis KW - Gliosis KW - Bromodesoxiuridina KW - Cannabinoides KW - Carbamatos KW - Caspasa 3 KW - Muerte celular KW - Proliferación celular KW - Colesterol KW - Endocannabinoides KW - Etanolaminas KW - Glucosa KW - Hipocampo KW - Hipotálamo KW - Microglía KW - Ácidos oléicos KW - Ácidos palmíticos KW - Ratas KW - Receptor cannabinoide CB1 KW - Triglicéridos KW - Amidohidrolasas KW - Apoptosis KW - Astrocitos KW - Benzamidas KW - Peso corporal KW - Cerebro KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Amidohydrolases KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis KW - Medical Subject Headings::Anatomy::Cells::Neuroglia::Astrocytes KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Benzamides KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight KW - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleosides::Deoxyribonucleosides::Deoxyuridine::Bromodeoxyuridine KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Terpenes::Cannabinoids KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Carboxylic Acids::Acids, Acyclic::Carbamates KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Intracellular Signaling Peptides and Proteins::Apoptosis Regulatory Proteins::Caspases KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation KW - Medical Subject Headings::Chemicals and Drugs::Polycyclic Compounds::Steroids::Cholestanes::Cholestenes::Cholesterol KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Endocannabinoids KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amines::Amino Alcohols::Ethanolamines KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Gliosis KW - Medical Subject Headings::Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose KW - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hippocampus KW - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain::Limbic System::Hypothalamus KW - Medical Subject Headings::Anatomy::Nervous System::Neuroglia::Microglia KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation::Neurogenesis KW - Medical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids, Unsaturated::Fatty Acids, Monounsaturated::Oleic Acids KW - Medical Subject Headings::Chemicals and Drugs::Lipids::Fatty Acids::Palmitic Acids KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, G-Protein-Coupled::Receptors, Cannabinoid::Receptor, Cannabinoid, CB1 KW - Medical Subject Headings::Chemicals and Drugs::Lipids::Glycerides::Triglycerides TI - Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothalamus and striatum in a negative energy context. TY - research article ER -