RT Journal Article
T1 Regenerative Therapies in Dry Eye Disease: From Growth Factors to Cell Therapy.
A1 Villatoro, Antonio J
A1 Fernández, Viviana
A1 Claros, Silvia
A1 Alcoholado, Cristina
A1 Cifuentes, Manuel
A1 Merayo-Lloves, Jesús
A1 Andrades, José A
A1 Becerra, José
K1 allogenic cell therapy
K1 dry eye
K1 growth factor
K1 keratoconjunctivitis sicca
K1 lacrimal gland
K1 mesenchymal stem cell
K1 regenerative medicine
AB Dry eye syndrome is a complex and insidious pathology with a high level of prevalence among the human population and with a consequently high impact on quality of life and economic cost. Currently, its treatment is symptomatic, mainly based on the control of lubrication and inflammation, with significant limitations. Therefore, the latest research is focused on the development of new biological strategies, with the aim of regenerating affected tissues, or at least restricting the progression of the disease, reducing scar tissue, and maintaining corneal transparency. Therapies range from growth factors and cytokines to the use of different cell sources, in particular mesenchymal stem cells, due to their multipotentiality, trophic, and immunomodulatory properties. We will review the state of the art and the latest advances and results of these promising treatments in this pathology.
YR 2017
FD 2017-10-28
LK http://hdl.handle.net/10668/11803
UL http://hdl.handle.net/10668/11803
LA en
DS RISalud
RD Apr 18, 2025