TY  - JOUR
AU  - Noren Hooten, Nicole
AU  - Martin-Montalvo, Alejandro
AU  - Dluzen, Douglas F.
AU  - Zhang, Yongqing
AU  - Bernier, Michel
AU  - Zonderman, Alan B.
AU  - Becker, Kevin G.
AU  - Gorospe, Myriam
AU  - de Cabo, Rafael
AU  - Evans, Michele K.
PY  - 2016
DO  - 10.1111/acel.12469
SN  - 1474-9718
UR  - http://hdl.handle.net/10668/18981
T2  - Aging cell
AB  - Metformin, an oral hypoglycemic agent, has been used for decades to treat type 2 diabetes mellitus. Recent studies indicate that mice treated with metformin live longer and have fewer manifestations of age-related chronic disease. However, the...
LA  - en
PB  - Wiley
KW  - aging
KW  - AUF1
KW  - caloric restriction
KW  - diabetes mellitus
KW  - microRNA
KW  - RNA-binding proteins
KW  - Messenger-rna decay
KW  - Life-span
KW  - Stress
KW  - Ampk
KW  - Phosphorylation
KW  - Mechanisms
KW  - Elegans
KW  - Pathway
KW  - Mir-34a
KW  - Binding
TI  - Metformin-mediated increase in DICER1 regulates microRNA expression and cellular senescence
TY  - research article
VL  - 15
ER  -