TY - JOUR AU - Pascual, Tomás AU - Oliveira, Mafalda AU - Ciruelos, Eva AU - Bellet Ezquerra, Meritxell AU - Saura, Cristina AU - Gavilá, Joaquin AU - Pernas, Sonia AU - Muñoz, Montserrat AU - Vidal, Maria J AU - Margelí Vila, Mireia AU - Cejalvo, Juan M AU - González-Farré, Blanca AU - Espinosa-Bravo, Martin AU - Cruz, Josefina AU - Salvador-Bofill, Francisco Javier AU - Guerra, Juan Antonio AU - Luna Barrera, Ana María AU - Arumi de Dios, Miriam AU - Esker, Stephen AU - Fan, Pang-Dian AU - Martínez-Sáez, Olga AU - Villacampa, Guillermo AU - Paré, Laia AU - Ferrero-Cafiero, Juan M AU - Villagrasa, Patricia AU - Prat, Aleix PY - 2021 DO - 10.3389/fonc.2021.638482 SN - 2234-943X UR - https://hdl.handle.net/10668/27194 T2 - Frontiers in oncology AB - Background: Preclinical data support a key role for the human epidermal growth factor receptor 3 (HER3) pathway in hormone receptor (HR)-positive breast cancer. Recently, new HER3 directed antibody drug conjugates have shown activity in breast cancer.... LA - en KW - Breast Cancer KW - CelTIL Score KW - ERBB3 KW - HER3 KW - HER3-DXd KW - U3-1402 KW - patritumab deruxtecan TI - SOLTI-1805 TOT-HER3 Study Concept: A Window-of-Opportunity Trial of Patritumab Deruxtecan, a HER3 Directed Antibody Drug Conjugate, in Patients With Early Breast Cancer. TY - research article VL - 11 ER -