TY - JOUR AU - Garrido-Rodriguez, Martín AU - Lopez-Lopez, Daniel AU - Ortuno, Francisco M. AU - Peña-Chilet, María AU - Muñoz, Eduardo AU - Calzado, Marco A. AU - Dopazo, Joaquin PY - 2021 DO - 10.1371/journal.pcbi.1008748 UR - http://hdl.handle.net/10668/4220 T2 - PLoS computational biology AB - MIGNON is a workflow for the analysis of RNA-Seq experiments, which not only efficiently manages the estimation of gene expression levels from raw sequencing reads, but also calls genomic variants present in the transcripts analyzed. Moreover, this is... LA - en PB - Public Library of Science KW - Transcriptome KW - RNA massive sequencing KW - RNA-seq KW - Workflow KW - Signaling pathways KW - Transcriptoma KW - Flujo de trabajo KW - Secuenciación de escopeta completa del transcriptoma KW - Medical Subject Headings::Phenomena and Processes::Mathematical Concepts::Algorithms KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor KW - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Computational Biology KW - Medical Subject Headings::Information Science::Information Science::Information Storage and Retrieval::Databases as Topic::Databases, Factual KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Gene Expression Profiling KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Sequence Analysis::High-Throughput Nucleotide Sequencing KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation KW - Medical Subject Headings::Information Science::Information Science::Computing Methodologies::Software KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Transcription, Genetic::Transcriptome KW - Medical Subject Headings::Information Science::Information Science::Systems Analysis::Workflow KW - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genomics KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction TI - A versatile workflow to integrate RNA-seq genomic and transcriptomic data into mechanistic models of signaling pathways TY - research article ER -