RT Journal Article T1 Clinical features and changes in epidemiology of infective endocarditis on pacemaker devices over a 27-year period (1987-2013). A1 Carrasco, Francisco A1 Anguita, Manuel A1 Ruiz, Martín A1 Castillo, Juan Carlos A1 Delgado, Mónica A1 Mesa, Dolores A1 Romo, Elias A1 Pan, Manuel A1 Suárez de Lezo, Jose K1 Cardiac resynchronization therapy K1 Device K1 Endocarditis K1 Implantable cardioverter-defibrillator K1 Infective endocarditis K1 Pacemaker AB Use of cardiac pacing devices has grown in recent years. Our aim was to evaluate changes in epidemiology and clinical features of infective endocarditis (IE) involving pacemaker devices in a large series of IE over the last 27 years (1987-2013). From 1987 to December 2013, 413 consecutive IE cases were diagnosed in our hospital. During this period, 7424 pacemaker devices were implanted (6917 pacemakers, 239 implantable cardiac defibrillators, 158 resynchronization devices, and 110 resynchronization/defibrillator devices). All consecutive cases of IE on pacemaker devices were included and analysed. Infective endocarditis on pacemaker devices represented 6.1% of all endocarditis cases (25 patients), affecting 3.6/1000 of all implanted pacemakers. Its proportion increased from 1.25% of all endocarditis in 1987-1993 to 4.08% in 1994-2000, 7.69% in 2001-2007 and 9.32% in 2008-2013 (P Infective endocarditis on pacemaker devices has shown an increasing incidence during the past decades, representing almost 10% of all IE in the last 6 years. This is a severe disease, with a high rate of severe complications and requiring removal of device in most cases. In spite of therapy, early mortality is high. YR 2015 FD 2015-12-24 LK http://hdl.handle.net/10668/9682 UL http://hdl.handle.net/10668/9682 LA en DS RISalud RD Apr 19, 2025