RT Journal Article T1 Transcatheter Aortic Valve Replacement in Pure Native Aortic Valve Regurgitation A1 Yoon, Sung-Han A1 Schmidt, Tobias A1 Bleiziffer, Sabine A1 Schofer, Niklas A1 Fiorina, Claudia A1 Munoz-Garcia, Antonio J. A1 Yzeiraj, Ermela A1 Amat-Santos, Ignacio J. A1 Tchetche, Didier A1 Jung, Christian A1 Fujita, Buntaro A1 Mangieri, Antonio A1 Deutsch, Marcus-Andre A1 Ubben, Timm A1 Deuschl, Florian A1 Kuwata, Shingo A1 De Biase, Chiara A1 Williams, Timothy A1 Dhoble, Abhijeet A1 Kim, Won-Keun A1 Ferrari, Enrico A1 Barbanti, Marco A1 Vollema, E. Mara A1 Miceli, Antonio A1 Giannin, Cristina A1 Attizzani, Guiherme F. A1 Kong, William K. F. A1 Gutierrez-Ibanes, Enrique A1 Jimenez Diaz, Victor Alfonso A1 Wijeysundera, Harindra C. A1 Kaneko, Hidehiro A1 Chakravarty, Tarun A1 Makar, Moody A1 Sievert, Horst A1 Hengstenberg, Christian A1 Prendergas, Bernard D. A1 Vincent, Flavien A1 Abdel-Wahab, Mohamed A1 Nombela-Franco, Luis A1 Silaschi, Miriam A1 Tarantini, Giuseppe A1 Butter, Christian A1 Ensminger, Stephan M. A1 Hildick-Smith, David A1 Petronio, Anna Sonia A1 Yin, Wei-Hsian A1 De Marco, Federico A1 Testa, Luca A1 Van Mieghem, Nicolas M. A1 Whisenant, Brian K. A1 Kuck, Karl-Heinz A1 Colombo, Antonio A1 Kar, Saibal A1 Moris, Cesar A1 Delgado, Victoria A1 Maisano, Francesco A1 Nietlispach, Fabian A1 Mack, Michael J. A1 Schofer, Joachim A1 Schaefer, Ulrich A1 Bax, Jeroen J. A1 Frerker, Christian A1 Latib, Azeem A1 Makkar, Raj R. K1 aortic regurgitation K1 transcatheter valve implantation K1 High-risk patients K1 Heart-valve K1 Transapical implantation K1 Stenosis K1 Experience K1 Outcomes K1 Prosthesis K1 Registry K1 System AB BACKGROUND Limited data exist about safety and efficacy of transcatheter aortic valve replacement (TAVR) in patients with pure native aortic regurgitation (AR).OBJECTIVES This study sought to compare the outcomes of TAVR with early-and new-generation devices in symptomatic patients with pure native AR.METHODS From the pure native AR TAVR multicenter registry, procedural and clinical outcomes were assessed according to VARC-2 criteria and compared between early-and new-generation devices.RESULTS A total of 331 patients with a mean STS score of 6.7 +/- 6.7 underwent TAVR. The early-and new-generation devices were used in 119 patients (36.0%) and 212 patients (64.0%), respectively. STS score tended to be lower in the new-generation device group (6.2 +/- 6.7 vs. 7.6 +/- 6.7; p = 0.08), but transfemoral access was more frequently used in the early-generation device group (87.4% vs. 60.8%; p = moderate (4.2% vs. 18.8%; p= moderate compared with those with post-procedural AR = moderate was independently associated with 1-year all-cause mortality (hazard ratio: 2.85; 95% confidence interval: 1.52 to 5.35; p = 0.001).CONCLUSIONS Compared with the early-generation devices, TAVR using the new-generation devices was associated with improved procedural outcomes in treating patients with pure native AR. In patients with pure native AR, significant post-procedural AR was independently associated with increased mortality. (C) 2017 by the American College of Cardiology Foundation. PB Elsevier science inc SN 0735-1097 YR 2017 FD 2017-12-05 LK https://hdl.handle.net/10668/26862 UL https://hdl.handle.net/10668/26862 LA en DS RISalud RD Apr 17, 2025