RT Journal Article
T1 Higher Proportion of Non-1-84 PTH Fragments in Peritoneal Dialysis Patients Compared to Hemodialysis Patients Using Solutions Containing 1.75 mmol/l Calcium.
A1 Sánchez-González, Carmen
A1 Gonzalez-Casaus, Maria Luisa
A1 Sellares, Víctor Lorenzo
A1 Albalate, Marta
A1 Torregrosa, José-Vicente
A1 Mas, Sebastian
A1 Ortiz, Alberto
A1 Rodriguez, Mariano
A1 Gonzalez-Parra, Emilio
K1 1-84PTH/7-84PTH ratio
K1 7-84PTH fragments
K1 PTH fragments
K1 low calcium dialysate
K1 low turnover bone disease
K1 non-1-84PTH fragments
K1 peritoneal dialysis
AB Background: The prevalence of low- turnover bone disease (LTBD) in peritoneal dialysis (PD) patients is higher than in hemodialysis (HD) patients. LTBD patients may be at risk for vascular calcification, and cardiovascular disease. Current therapy for chronic kidney disease metabolic bone disorders (CKD-MBD) is guided by biochemical parameters, as bone biopsy is not used in routine clinical care. Methods: We assessed intact PTH (iPTH: 1-84PTH plus non-1-84PTH), 1-84PTH, and the 1-84PTH/non-1-84PTH ratio in 129 hemodialysis and 73 PD prevalent patients dialyzed with solutions containing 1.75 mmol/L calcium. Results: Hemodialysis and PD patients presented similar iPTH and tCa values and prevalence of putative LTBD as defined according to KDOQI iPTH cut-off levels or 1-84 PTH levels. However, iCa accounted for a higher percentage of tCa in PD (53%) than in hemodialysis (39%) p
SN 1664-042X
YR 2018
FD 2018-11-20
LK http://hdl.handle.net/10668/13289
UL http://hdl.handle.net/10668/13289
LA en
DS RISalud
RD Apr 6, 2025