TY  - JOUR
AU  - Walford, Geoffrey A
AU  - Colomo, Natalia
AU  - Todd, Jennifer N
AU  - Billings, Liana K
AU  - Fernandez, Marlene
AU  - Chamarthi, Bindu
AU  - Warner, A Sofia
AU  - Davis, Jaclyn
AU  - Littleton, Katherine R
AU  - Hernandez, Alicia M
AU  - Fanelli, Rebecca R
AU  - Lanier, Amelia
AU  - Barbato, Corinne
AU  - Ackerman, Rachel J
AU  - Khan, Sabina Q
AU  - Bui, Rosa
AU  - Garber, Laurel
AU  - Stolerman, Elliot S
AU  - Moore, Allan F
AU  - Huang, Chunmei
AU  - Kaur, Varinderpal
AU  - Harden, Maegan
AU  - Taylor, Andrew
AU  - Chen, Ling
AU  - Manning, Alisa K
AU  - Huang, Paul
AU  - Wexler, Deborah
AU  - McCarthy, Rita M
AU  - Lo, Janet
AU  - Thomas, Melissa K
AU  - Grant, Richard W
AU  - Goldfine, Allison
AU  - Hudson, Margo S
AU  - Florez, Jose C
PY  - 2015
DO  - 10.1371/journal.pone.0121553
UR  - http://hdl.handle.net/10668/2332
T2  - PloS One
AB  - OBJECTIVEGenome-wide association studies have uncovered a large number of genetic variants associated with type 2 diabetes or related phenotypes. In many cases the causal gene or polymorphism has not been identified, and its impact on response to...
LA  - en
PB  - Public Library of Science
KW  - Alelos
KW  - Glucosa sanguínea
KW  - Diabetes Mellitus, Tipo II
KW  - Predisposición genética a la enfermedad
KW  - glipicida
KW  - Prueba de tolerancia a la glucosa
KW  - Insulina
KW  - Biomarcadores
KW  - Hipoglicemiantes
KW  - Fenotipo
KW  - Polimorfismo de nucleótido único
KW  - Proteína 2 similar al factor de transcripción 7
KW  - Resultado del tratamiento
KW  - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers
KW  - Medical Subject Headings::Chemicals and Drugs::Carbohydrates::Monosaccharides::Hexoses::Glucose::Blood Glucose
KW  - Medical Subject Headings::Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 2
KW  - Medical Subject Headings::Check Tags::Female
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype::Genetic Predisposition to Disease
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Sulfur Compounds::Sulfones::Sulfonylurea Compounds::Glipizide
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Clinical Laboratory Techniques::Clinical Chemistry Tests::Blood Chemical Analysis::Glucose Tolerance Test
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hypoglycemic Agents
KW  - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Peptide Hormones::Pancreatic Hormones::Insulins
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amidines::Guanidines::Biguanides::Metformin
KW  - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
KW  - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Pharmacology::Pharmacogenetics
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Polymorphism, Single Nucleotide
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors::TCF Transcription Factors::Transcription Factor 7-Like 2 Protein
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome
KW  - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult
TI  - The study to understand the genetics of the acute response to metformin and glipizide in humans (SUGAR-MGH): design of a pharmacogenetic resource for type 2 diabetes.
TY  - research article
ER  -