TY  - JOUR
AU  - Guerra-Librero, Ana
AU  - Fernandez-Gil, Beatriz I.
AU  - Florido, Javier
AU  - Martinez-Ruiz, Laura
AU  - Rodríguez-Santana, César
AU  - Shen, Ying-Qiang
AU  - García-Verdugo, José M.
AU  - López-Rodríguez, Alba
AU  - Rusanova, Iryna
AU  - Quiñones-Hinojosa, Alfredo
AU  - Acuña-Castroviejo, Darío
AU  - Marruecos, Jordi
AU  - De Haro, Tomás
AU  - Escames, Germaine
PY  - 2021
DO  - 10.3390/antiox10040603
UR  - http://hdl.handle.net/10668/3992
T2  - Antioxidants
AB  - Metabolic reprogramming, which is characteristic of cancer cells that rapidly adapt to the hypoxic microenvironment and is crucial for tumor growth and metastasis, is recognized as one of the major mechanisms underlying therapeutic resistance....
LA  - en
PB  - MDPI
KW  - Melatonin
KW  - Head and neck cancer cells
KW  - Mitochondria
KW  - OXPHOS
KW  - Glycolysis
KW  - Mitophagy
KW  - Apoptosis
KW  - Free radicals
KW  - Melatonina
KW  - Mitocondrias
KW  - Glucólisis
KW  - Mitofagia
KW  - Radicales libres
KW  - Neoplasias de cabeza y cuello
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Free Radicals::Reactive Oxygen Species
KW  - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Melatonin
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance::Drug Resistance, Neoplasm
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Phosphorylation::Oxidative Phosphorylation
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Receptors, Cytoplasmic and Nuclear::Receptors, Melatonin
KW  - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Subcellular Fractions::Mitochondria
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Head and Neck Neoplasms
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Carbohydrate Metabolism::Glycolysis
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line
TI  - Melatonin Targets Metabolism in Head and Neck Cancer Cells by Regulating Mitochondrial Structure and Function
TY  - research article
ER  -