RT Journal Article T1 Pancreatobiliary maljunction: association with gallbladder cancer. A1 Garzón Benavides, Marta A1 Núñez Ortiz, Andrea A1 López Ruiz, Teófilo A1 Cepeda Franco, Carmen A1 Gómez Izquierdo, Lourdes AB Pancreatobiliary maljunction is a rare disease characterized by the junction of the pancreatic and biliary ducts outside of the duodenal wall, which normally results in a large common duct. As a result, there is a greater risk of acute pancreatitis and cancer of the gallbladder and biliary tract. We present the case of a 43-year-old female diagnosed with a pancreatobiliary maljunction and an associated stenosis of the bile duct, secondary to an episode of acute pancreatitis. She underwent several endoscopic retrograde cholangiopancreatography procedures over the course of three years, without improvement of the stenosis, and therefore a surgical approach was taken. Prior to the surgical intervention, magnetic resonance imaging showed the presence of an 11-mm polyp in the gallbladder. A histological study of the surgical sample identified intramucosal adenocarcinoma over a tubular adenoma of the gallbladder. Pancreatobiliary maljunction can be considered as a premalignant entity due to the risk of developing cancer of the biliary tree and gallbladder. Therefore, these patients should undergo a prophylactic intervention, despite being asymptomatic. SN 1130-0108 YR 2019 FD 2019 LK http://hdl.handle.net/10668/14140 UL http://hdl.handle.net/10668/14140 LA en DS RISalud RD Apr 10, 2025