RT Journal Article
T1 Automatic Integration of Clinical and Genetic Data Using cBioPortal.
A1 Brunner, Mauricio
A1 Mullen, Lucas
A1 Jauk, Federico
A1 Oliver, Javier
A1 Cayol, Federico
A1 Minata, José
A1 Herrera, Victor
A1 Pavicic, Walter
A1 Luna, Daniel
A1 Risk, Marcelo
A1 Garcia Rivello, Hernan
A1 Benitez, Sonia
K1 Genomics
K1 Medical Informatics
K1 Precision Medicine
AB Precision medicine seeks to improve the prevention, diagnosis and treatment of patients based on genetic characteristics unique to each person. In oncology, therapeutic decisions have been established based on the genomic characteristics of each patient's tumor. Data integration is key for the successful implementation of precision medicine since it is necessary for both studying a large volume of data from different sources and working with an interdisciplinary and translational vision. In this work, a bioinformatic process was successfully implemented that allows the integration of patients' genomic data, from two molecular biology laboratories, with their clinical data provided by their electronic medical records. For this, the REDCap data capture software, the cBioPortal visualization and analysis software, and a computer tool developed to automate the processing and annotation of the information in REDCap were used to be included in cBioPortal, for the "Map of Tumor Genomic Actionability of Argentina" project.
YR 2022
FD 2022
LK http://hdl.handle.net/10668/20516
UL http://hdl.handle.net/10668/20516
LA en
DS RISalud
RD Apr 6, 2025