RT Generic
T1 The Effect of Therapeutic Hypothermia after Cardiac Arrest on the Neurological Outcome and Survival-A Systematic Review of RCTs Published between 2016 and 2020
A1 Colls Garrido, Christian
A1 Riquelme Gallego, Blanca
A1 Sanchez Garcia, Juan Carlos
A1 Cortes Martin, Jonathan
A1 Montiel Troya, Maria
A1 Rodriguez Blanque, Raquel
K1 induced hypothermia
K1 cardiac arrest
K1 survival rate
K1 critical care
K1 Targeted temperature management
K1 International liaison committee
K1 American-heart-association
K1 Comatose survivors
K1 Cardiopulmonary-resuscitation
K1 Cold saline
K1 Care
K1 33-degrees-c
K1 Trial
K1 Life
AB Therapeutic hypothermia is a treatment used for patients who have suffered cardiorespiratory arrest and remain conscious after the recovery of spontaneous circulation. However, its effectiveness is controversial. The objective of this systematic review is to summarize the scientific evidence available about the effect of therapeutic hypothermia on neurological status and survival in this type of patients. Methodology: A primary search in CINAHL, CUIDEN, Pubmed, Web of Science, and Scopus databases was carried out. Randomized clinical trials (RCT) published from 2016 to 2020 were selected. Results: 17 studies were selected for inclusion and most relevant data were extracted. Methodological quality was assessed by the RoB tool. Conclusions: Although therapeutic hypothermia is a safe technique with few adverse and manageable effects, it has not shown to improve survival rate and neurological status of adult nor pediatric patients. It is possible that its positive effect on neuroprotection could be achieved only by preventing hyperthermia although further investigation is needed.
PB Mdpi
YR 2021
FD 2021-11-01
LK https://hdl.handle.net/10668/26002
UL https://hdl.handle.net/10668/26002
LA en
DS RISalud
RD Apr 8, 2025