RT Journal Article
T1 Quality of Life in a Cohort of 1078 Women Diagnosed with Breast Cancer in Spain: 7-Year Follow-Up Results in the MCC-Spain Study.
A1 Alonso-Molero, Jéssica
A1 Dierssen-Sotos, Trinidad
A1 Gomez-Acebo, Ines
A1 Fernandez de Larrea Baz, Nerea
A1 Guevara, Marcela
A1 Amiano, Pilar
A1 Castaño-Vinyals, Gemma
A1 Fernandez-Villa, Tania
A1 Moreno, Victor
A1 Bayo, Juan
A1 Molina-Barceloa, Ana
A1 Fernández-Ortíz, María
A1 Suarez-Calleja, Claudia
A1 Marcos-Gragera, Rafael
A1 Castells, Xavier
A1 Gil-Majuelo, Leire
A1 Ardanaz, Eva
A1 Pérez-Gómez, Beatriz
A1 Kogevinas, Manolis
A1 Pollán, Marina
A1 Llorca, Javier
K1 FBSI
K1 SF-12
K1 breast cancer
K1 educational level
K1 quality of life
AB Breast cancer is the most frequent cause of tumors and net survival is increasing. Achieving a higher survival probability reinforces the importance of studying health-related quality of life (HR-QoL). The main aim of this work is to test the relationship between different sociodemographic, clinical and tumor-intrinsic characteristics, and treatment received with HR-QoL measured using SF-12 and the FACT/NCCN (National Comprehensive Cancer Network/Functional Assessment of Cancer Therapy) Breast Symptom Index (FBSI). Women with breast cancer recruited between 2008 and 2013 and followed-up until 2017-2018 in a prospective cohort answered two HR-QoL surveys: the SF-12 and FBSI. The scores obtained were related to woman and tumor characteristics using linear regression models. The telephone survey was answered by 1078 women out of 1685 with medical record follow-up (64%). Increases in all three HR-QoL scores were associated with higher educational level. The score differences between women with university qualifications and women with no schooling were 5.43 for PCS-12, 6.13 for MCS-12 and 4.29 for FBSI. Histological grade at diagnosis and recurrence in the follow-up displayed a significant association with mental and physical HR-QoL, respectively. First-line treatment received was not associated with HR-QoL scores. On the other hand, most tumor characteristics were not associated with HR-QoL. As breast cancer survival is improving, further studies are needed to ascertain if these differences still hold in the long run.
YR 2020
FD 2020-11-13
LK http://hdl.handle.net/10668/16621
UL http://hdl.handle.net/10668/16621
LA en
DS RISalud
RD Apr 6, 2025