%0 Journal Article
%A Riazzo, Cristina
%A Pérez-Ruiz, Mercedes
%A Sanbonmatsu-Gámez, Sara
%A Pedrosa-Corral, Irene
%A Gutiérrez-Fernández, José
%A Navarro-Marí, José-María
%T Analytical performance of the Alere™ i Influenza A&B assay for the rapid detection of influenza viruses.
%D 2015
%U http://hdl.handle.net/10668/9647
%X The analytical performance of the new Alere™ i Influenza A&B kit (AL-Flu) assay, based on isothermal nucleic acids amplification, was evaluated and compared with an antigen detection method, SD Bioline Influenza Virus Antigen Test (SDB), and an automated real-time RT-PCR, Simplexa™ Flu A/B & VRS Direct assay (SPX), for detection of influenza viruses. An "in-house" RT-PCR was used as the reference method. Sensitivity of AL-Flu, SDB, and SPX was 71.7%, 34.8%, and 100%, respectively. Specificity was 100% for all techniques. The turnaround time was 13min for AL-Flu, 15min for SDB, and 75min for SPX. The Alere™ i Influenza A&B assay is an optimal point-of-care assay for influenza diagnosis in clinical emergency settings, and is more sensitive and specific than antigen detection methods.
%K Detección rápida
%K Gripe
%K Influenza
%K Molecular testing
%K Método molecular
%K Rapid detection
%~