TY - JOUR AU - Shen, Xianli AU - Burguillos, Miguel A AU - Osman, Ahmed M AU - Frijhoff, Jeroen AU - Carrillo-Jiménez, Alejandro AU - Kanatani, Sachie AU - Augsten, Martin AU - Saidi, Dalel AU - Rodhe, Johanna AU - Kavanagh, Edel AU - Rongvaux, Anthony AU - Rraklli, Vilma AU - Nyman, Ulrika AU - Holmberg, Johan AU - Östman, Arne AU - Flavell, Richard A AU - Barragan, Antonio AU - Venero, Jose Luis AU - Blomgren, Klas AU - Joseph, Bertrand PY - 2016 DO - 10.1038/ni.3545 UR - http://hdl.handle.net/10668/10436 T2 - Nature immunology AB - Glioma cells recruit and exploit microglia (the resident immune cells of the brain) for their proliferation and invasion ability. The underlying molecular mechanism used by glioma cells to transform microglia into a tumor-supporting phenotype has... LA - en KW - Animals KW - Caspase 3 KW - Cell Line, Tumor KW - Cell Movement KW - Disease Models, Animal KW - Enzyme Activation KW - Gene Knockdown Techniques KW - Glioma KW - Heterografts KW - Humans KW - Male KW - Mice KW - Microglia KW - Mitochondria KW - Mitochondrial Proteins KW - Nitric Oxide Synthase Type II KW - Phenotype KW - Thioredoxins KW - Tumor Burden TI - Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype. TY - research article VL - 17 ER -