TY  - JOUR
AU  - Chen, Lubin
AU  - Wimalasena, Nivanthika K
AU  - Shim, Jaehoon
AU  - Han, Chongyang
AU  - Lee, Seong-Il
AU  - Gonzalez-Cano, Rafael
AU  - Estacion, Mark
AU  - Faber, Catharina G
AU  - Lauria, Giuseppe
AU  - Dib-Hajj, Sulayman D
AU  - Woolf, Clifford J
AU  - Waxman, Stephen G
PY  - 2021
DO  - 10.1097/j.pain.0000000000002171
UR  - https://hdl.handle.net/10668/27126
T2  - Pain
AB  - Small-fiber neuropathy (SFN), characterized by distal unmyelinated or thinly myelinated fiber loss, produces a combination of sensory dysfunction and neuropathic pain. Gain-of-function variants in the sodium channel Nav1.7 that produce dorsal root...
LA  - en
KW  - Animals
KW  - Gain of Function Mutation
KW  - Ganglia, Spinal
KW  - Humans
KW  - Mice
KW  - NAV1.7 Voltage-Gated Sodium Channel
KW  - Phenotype
KW  - Sensory Receptor Cells
TI  - Two independent mouse lines carrying the Nav1.7 I228M gain-of-function variant display dorsal root ganglion neuron hyperexcitability but a minimal pain phenotype.
TY  - research article
VL  - 162
ER  -