RT Journal Article T1 DSM-5 Attenuated Psychosis Syndrome in Adolescents Hospitalized With Non-psychotic Psychiatric Disorders. A1 Salazar de Pablo, Gonzalo A1 Guinart, Daniel A1 Cornblatt, Barbara A A1 Auther, Andrea M A1 Carrión, Ricardo E A1 Carbon, Maren A1 Jiménez-Fernández, Sara A1 Vernal, Ditte L A1 Walitza, Susanne A1 Gerstenberg, Miriam A1 Saba, Riccardo A1 Lo Cascio, Nella A1 Brandizzi, Martina A1 Arango, Celso A1 Moreno, Carmen A1 Van Meter, Anna A1 Fusar-Poli, Paolo A1 Correll, Christoph U K1 Attenuated Psychosis Syndrome (APS) K1 adolescence K1 epidemiology K1 prevention K1 psychosis K1 risk AB Introduction: Although attenuated psychotic symptoms often occur for the first time during adolescence, studies focusing on adolescents are scarce. Attenuated psychotic symptoms form the criteria to identify individuals at increased clinical risk of developing psychosis. The study of individuals with these symptoms has led to the release of the DSM-5 diagnosis of Attenuated Psychosis Syndrome (APS) as a condition for further research. We aimed to characterize and compare hospitalized adolescents with DSM-5-APS diagnosis vs. hospitalized adolescents without a DSM-5-APS diagnosis. Methods: Interviewing help-seeking, hospitalized adolescents (aged 12-18 years) and their caregivers independently with established research instruments, we (1) evaluated the presence of APS among non-psychotic adolescents, (2) characterized and compared APS and non-APS individuals regarding sociodemographic, illness and intervention characteristics, (3) correlated psychopathology with levels of functioning and severity of illness and (4) investigated the influence of individual clinical, functional and comorbidity variables on the likelihood of participants to be diagnosed with APS. Results: Among 248 consecutively recruited adolescents (age=15.4 ± 1.5 years, females = 69.6%) with non-psychotic psychiatric disorders, 65 (26.2%) fulfilled APS criteria and 183 (73.8%) did not fulfill them. Adolescents with APS had higher number of psychiatric disorders than non-APS adolescents (3.5 vs. 2.4, p SN 1664-0640 YR 2020 FD 2020-10-21 LK http://hdl.handle.net/10668/16607 UL http://hdl.handle.net/10668/16607 LA en DS RISalud RD Apr 9, 2025