TY  - JOUR
AU  - Rodríguez-Núñez, Pablo
AU  - Romero-Pérez, Laura
AU  - Amaral, Ana T
AU  - Puerto-Camacho, Pilar
AU  - Jordán, Carmen
AU  - Marcilla, David
AU  - Grünewald, Thomas Gp
AU  - Alonso, Javier
AU  - de Alava, Enrique
AU  - Díaz-Martín, Juan
PY  - 2020
DO  - 10.1002/path.5379
UR  - http://hdl.handle.net/10668/14888
T2  - The Journal of pathology
AB  - YAP1 and TAZ (WWTR1) oncoproteins are the final transducers of the Hippo tumor suppressor pathway. Deregulation of the pathway leads to YAP1/TAZ activation fostering tumorigenesis in multiple malignant tumor types, including sarcoma. However,...
LA  - en
KW  - Ewing sarcoma
KW  - Hippo pathway
KW  - immunohistochemistry
KW  - metastasis
KW  - transcriptional signatures
KW  - Adult
KW  - Aged
KW  - Cell Line, Tumor
KW  - Disease Progression
KW  - Female
KW  - Gene Expression Regulation, Neoplastic
KW  - Hippo Signaling Pathway
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Neoplasm Recurrence, Local
KW  - Oncogene Proteins, Fusion
KW  - Protein Serine-Threonine Kinases
KW  - Proto-Oncogene Protein c-fli-1
KW  - RNA-Binding Protein EWS
KW  - Sarcoma, Ewing
KW  - Signal Transduction
KW  - Trans-Activators
KW  - Transcriptional Coactivator with PDZ-Binding Motif Proteins
TI  - Hippo pathway effectors YAP1/TAZ induce an EWS-FLI1-opposing gene signature and associate with disease progression in Ewing sarcoma.
TY  - research article
VL  - 250
ER  -