RT Journal Article
T1 Salivary Biomarkers and Their Application in the Diagnosis and Monitoring of the Most Common Oral Pathologies
A1 Melguizo-Rodríguez, Lucía
A1 Costela-Ruiz, Victor J.
A1 Manzano-Moreno, Francisco Javier
A1 Ruiz, Concepción
A1 Illescas-Montes, Rebeca
K1 Salivary biomarker
K1 Cytokines
K1 Oral pathology
K1 Diagnosis
K1 Saliva
K1 Biomarcadores
K1 Citocinas
K1 Patología bucal
K1 Diagnóstico
AB Saliva is a highly versatile biological fluid that is easy to gather in a non-invasive manner-and the results of its analysis complement clinical and histopathological findings in the diagnosis of multiple diseases. The objective of this review was to offer an update on the contribution of salivary biomarkers to the diagnosis and prognosis of diseases of the oral cavity, including oral lichen planus, periodontitis, Sjögren's syndrome, oral leukoplakia, peri-implantitis, and medication-related osteonecrosis of the jaw. Salivary biomarkers such as interleukins, growth factors, enzymes, and other biomolecules have proven useful in the diagnosis and follow-up of these diseases, facilitating the early evaluation of malignization risk and the monitoring of disease progression and response to treatment. However, further studies are required to identify new biomarkers and verify their reported role in the diagnosis and/or prognosis of oral diseases.
PB MDPI
YR 2020
FD 2020-07-21
LK http://hdl.handle.net/10668/3673
UL http://hdl.handle.net/10668/3673
LA en
NO Melguizo-Rodríguez L, Costela-Ruiz VJ, Manzano-Moreno FJ, Ruiz C, Illescas-Montes R. Salivary Biomarkers and Their Application in the Diagnosis and Monitoring of the Most Common Oral Pathologies. Int J Mol Sci. 2020 Jul 21;21(14):5173
DS RISalud
RD Apr 7, 2025