TY - JOUR AU - Flores, M Luz AU - Castilla, Carolina AU - Gasca, Jessica AU - Medina, Rafael AU - Pérez-Valderrama, Begoña AU - Romero, Francisco AU - Japón, Miguel A AU - Sáez, Carmen PY - 2016 DO - 10.1158/1535-7163.MCT-15-0951 UR - http://hdl.handle.net/10668/10102 T2 - Molecular cancer therapeutics AB - Prostate cancer is the leading cause of cancer-related death among men in developed countries. Although castration therapy is initially effective, prostate cancers progress to hormone-refractory disease and in this case taxane-based chemotherapy is... LA - en KW - Antineoplastic Agents, Phytogenic KW - Apoptosis KW - Aurora Kinase A KW - Cell Cycle Checkpoints KW - Cell Line, Tumor KW - Chromones KW - Drug Resistance, Neoplasm KW - Gene Expression KW - Gene Silencing KW - Humans KW - Male KW - Mitosis KW - Models, Biological KW - Morpholines KW - Myeloid Cell Leukemia Sequence 1 Protein KW - Paclitaxel KW - Prostatic Neoplasms KW - Protein Kinase C-delta KW - Proto-Oncogene Proteins c-akt KW - Proto-Oncogene Proteins c-bcl-2 KW - Wnt Signaling Pathway KW - beta Catenin TI - Loss of PKCδ Induces Prostate Cancer Resistance to Paclitaxel through Activation of Wnt/β-Catenin Pathway and Mcl-1 Accumulation. TY - research article VL - 15 ER -