RT Journal Article
T1 Elderly Population with COVID-19 and the Accuracy of Clinical Scales and D-Dimer for Pulmonary Embolism: The OCTA-COVID Study
A1 Quezada-Feijoo, Maribel
A1 Ramos, Monica
A1 Lozano-Montoya, Isabel
A1 Sarro, Monica
A1 Muinos, Veronica Cabo
A1 Ayala, Rocio
A1 Gomez-Pavon, Francisco J.
A1 Toro, Rocio
K1 pulmonary embolism
K1 Wells scale
K1 Geneva scale
K1 COVID-19
K1 older patients
K1 Revised geneva score
K1 Venous thromboembolism
K1 Prediction rules
K1 Wells score
K1 Probability
K1 Management
K1 Diagnosis
K1 Models
AB Background: Elderly COVID-19 patients have a high risk of pulmonary embolism (PE), but factors that predict PE are unknown in this population. This study assessed the Wells and revised Geneva scoring systems as predictors of PE and their relationships with D-dimer (DD) in this population. Methods: This was a longitudinal, observational study that included patients & GE;75 years old with COVID-19 and suspected PE. The performances of the Wells score, revised Geneva score and DD levels were assessed. The combinations of the DD level and the clinical scales were evaluated using positive rules for higher specificity. Results: Among 305 patients included in the OCTA-COVID study cohort, 50 had suspected PE based on computed tomography pulmonary arteriography (CTPA), and the prevalence was 5.6%. The frequencies of PE in the low-, intermediate- and high-probability categories were 5.9%, 88.2% and 5.9% for the Geneva model and 35.3%, 58.8% and 5.9% for the Wells model, respectively. The DD median was higher in the PE group (4.33 mg/L; interquartile range (IQR) 2.40-7.17) than in the no PE group (1.39 mg/L; IQR 1.01-2.75) (p  4.33 mg/L has an increased specificity, which can discriminate false positives. The addition of the DD and the clinical probability scales increases the specificity and negative predictive value, which helps to avoid unnecessary invasive tests in this population.
PB Mdpi
YR 2021
FD 2021-11-01
LK https://hdl.handle.net/10668/25241
UL https://hdl.handle.net/10668/25241
LA en
DS RISalud
RD Apr 17, 2025