RT Journal Article
T1 Metallofluorescent Nanoparticles for Multimodal Applications
A1 Delgado-Gonzalez, Antonio
A1 Garcia-Fernandez, Emilio
A1 Valero, Teresa
A1 Cano-Cortes, M. Victoria
A1 Ruedas-Rama, Maria J.
A1 Unciti-Broceta, Asier
A1 Sanchez-Martin, Rosario M.
A1 Diaz-Mochon, Juan J.
A1 Orte, Angel
K1 Gold nanoparticles
K1 Living cells
K1 Dyes
AB Herein, we describe the synthesis and application of cross-linked polystyrene-based dual-function nano- and microparticles containing both fluorescent tags and metals. Despite containing a single dye, these particles exhibit a characteristic dual-band fluorescence emission. Moreover, these particles can be combined with different metal ions to obtain hybrid metallofluorescent particles. We demonstrate that these particles are easily nanofected into living cells, allowing them to be used for effective fingerprinting in multimodal fluorescence-based and mass spectrometry-based flow cytometry experiments. Likewise, the in situ reductions of the metal ions enable other potential uses of the particles as heterogeneous catalysts.
PB Amer chemical soc
SN 2470-1343
YR 2018
FD 2018-01-01
LK http://hdl.handle.net/10668/18899
UL http://hdl.handle.net/10668/18899
LA en
DS RISalud
RD Apr 10, 2025