RT Journal Article
T1 Evolution of corneal epithelial remodeling after myopic laser in situ keratomileusis surgery measured by anterior segment optical coherence tomography combined with Placido disk.
A1 Díaz-Bernal, José
A1 García-Basterra, Ignacio
A1 Mora-Castilla, José
A1 Nguyen, Annie
A1 Fernandez-Barrientos, Yolanda
A1 Guerrero, Antonio M
K1 Corneal epithelium
K1 keratomileusis
K1 laser in situ
K1 myopia
K1 optical coherence tomography
K1 refractive surgeries procedures
AB To investigate patterns of short- and long-term variations in corneal epithelial thickness (CET) after myopic laser in situ keratomileusis (LASIK) using anterior segment optical coherence tomography (AS-OCT) combined with Placido disk-based topography. In this retrospective study, 36 subjects (72 eyes) who underwent LASIK myopic surgery and 53 healthy subjects (106 eyes) who served as controls were enrolled. AS-OCT (MS-39) was performed in all patients before, 1 day, 1 month, and 6 months after surgery. Statistical analysis was performed to analyze CET changes over time after LASIK and to detect patterns of definitive CET remodeling compared to healthy subjects. Multivariate analysis was performed to look for possible predictors of final CET. There was no statistically significant difference between groups in terms of demographic and anterior segment parameters (all P > 0.05). After LASIK, all sectors and rings got thicker over time (1.62-8.32 μm; P  0.05). After LASIK, all sectors and rings got thicker over time (1.62-8.32 μm; P  0.05). None of the clinical variables studied, including diopters corrected, were found to be correlated with final CET (P > 0.05). Independent of anterior segment parameters and diopters corrected, CET becomes thicker after LASIK surgery. Central and inner ring sectors thicken more than those more peripheral. CET remodeling after myopic LASIK should be taken into consideration when planning refractive surgery.
YR 2021
FD 2021
LK https://hdl.handle.net/10668/26924
UL https://hdl.handle.net/10668/26924
LA en
DS RISalud
RD Apr 6, 2025