TY - JOUR AU - Verdugo, Elena AU - Puerto, Iker AU - Medina, Miguel Ángel PY - 2022 DO - 10.1002/cac2.12361 UR - http://hdl.handle.net/10668/20952 T2 - Cancer communications (London, England) AB - Glioblastoma multiforme (GBM) is the most aggressive and common malignant primary brain tumor. Patients with GBM often have poor prognoses, with a median survival of ∼15 months. Enhanced understanding of the molecular biology of central nervous system... LA - en KW - cancer molecular biology KW - diagnosis KW - glioblastoma multiforme KW - ongoing clinical trials KW - targeted therapy KW - tumor heterogeneity KW - tumor metabolism KW - Humans KW - Glioblastoma KW - Proto-Oncogene Proteins c-akt KW - Phosphatidylinositol 3-Kinases KW - TOR Serine-Threonine Kinases KW - Molecular Biology KW - Tumor Microenvironment TI - An update on the molecular biology of glioblastoma, with clinical implications and progress in its treatment. TY - research article VL - 42 ER -