TY - JOUR AU - de la Ballina, Laura R AU - Cano-Crespo, Sara AU - González-Muñoz, Elena AU - Bial, Susanna AU - Estrach, Soline AU - Cailleteau, Laurence AU - Tissot, Floriane AU - Daniel, Hannelore AU - Zorzano, Antonio AU - Ginsberg, Mark H AU - Palacín, Manuel AU - Féral, Chloé C PY - 2016 DO - 10.1074/jbc.M115.704254 UR - http://hdl.handle.net/10668/9898 T2 - The Journal of biological chemistry AB - CD98hc functions as an amino acid (AA) transporter (together with another subunit) and integrin signaling enhancer. It is overexpressed in highly proliferative cells in both physiological and pathological conditions. CD98hc deletion induces strong... LA - en KW - SLC3A2/CD98hc/4F2hc KW - SLC7 family KW - amino acid transport KW - cell proliferation KW - oxidative stress KW - peptide transport KW - stress response KW - Amino Acid Transport System y+ KW - Amino Acid Transport System y+L KW - Amino Acids KW - Animals KW - Biological Transport, Active KW - Cell Differentiation KW - Cell Line KW - Cell Proliferation KW - Cell Survival KW - Fusion Regulatory Protein 1, Heavy Chain KW - Fusion Regulatory Protein 1, Light Chains KW - Gene Deletion KW - Mice KW - Mouse Embryonic Stem Cells KW - Oxidative Stress KW - Reactive Oxygen Species TI - Amino Acid Transport Associated to Cluster of Differentiation 98 Heavy Chain (CD98hc) Is at the Cross-road of Oxidative Stress and Amino Acid Availability. TY - research article VL - 291 ER -