RT Journal Article T1 Rationale and design of a multicenter, international and collaborative Coronary Artery Aneurysm Registry (CAAR). A1 Núñez-Gil, Iván J A1 Nombela-Franco, Luis A1 Bagur, Rodrigo A1 Bollati, Mario A1 Cerrato, Enrico A1 Alfonso, Emilio A1 Liebetrau, Christoph A1 De la Torre Hernandez, José María A1 Camacho, Benjamín A1 Mila, Rafael A1 Amat-Santos, Ignacio J A1 Alfonso, Fernando A1 Rodríguez-Olivares, Ramón A1 Camacho Freire, Santiago J A1 Lozano, Íñigo A1 Jiménez Díaz, Víctor Alfonso A1 Piraino, Davide A1 Latini, Roberto Adriano A1 Feltes, Gisela A1 Linares, Jose Antonio A1 Mancone, Massimo A1 Ielasi, Alfonso A1 Sánchez-Grande Flecha, Alejandro A1 Fernández Cisnal, Agustín A1 Ugo, Fabrizio A1 Jiménez Mazuecos, Jesús M A1 Omedè, Pierluigi A1 Pavani, Marco A1 Villablanca, Pedro A A1 Louka, Boshra F A1 Fernández-Ortiz, Antonio A1 CAAR Investigators, K1 CAAR K1 Coronary Aneurysm K1 Epidemiology K1 Prognosis K1 Registry AB Coronary artery aneurysm is defined as a coronary dilation that exceeds the diameter of adjacent segments or the diameter of the patient's largest normal coronary vessel by 1.5×. It is an uncommon disease that has been diagnosed with increasing frequency since the widespread appearance of coronary angiography. The published incidence varies from 1.5% to 5%, suggesting male dominance and a predilection for the right coronary artery. Although several causes have been described, atherosclerosis accounts for ≥50% of coronary aneurysms in adults. Reported complications include thrombosis and distal embolization, rupture, and vasospasm, causing ischemia, heart failure, or arrhythmias. The natural history and prognosis remain unknown, as definitive data are scarce. Controversies persist regarding the use of medical management (antithrombotic therapy) or interventional/surgical procedures. Only some case reports or small case series are available about this condition. The Coronary Artery Aneurysm Registry (CAAR; http://www.ClinicalTrials.gov NCT02563626) is a multicenter international ambispective registry that aims to provide insights on anatomic, epidemiologic, and clinical aspects of this substantially unknown entity. In addition, the registry will assess management strategies (conservative, interventional, or surgical) and their short- and long-term results in a large cohort of patients. ClinicalTrials.gov. Unique identifier: NCT02563626. YR 2017 FD 2017-03-24 LK http://hdl.handle.net/10668/10994 UL http://hdl.handle.net/10668/10994 LA en DS RISalud RD Apr 7, 2025