RT Journal Article
T1 Impact of Treating Asymptomatic Bacteriuria in Kidney Transplant Recipients: A Prospective Cohort Study.
A1 Fontserè, Sara
A1 Infante-Domínguez, Carmen
A1 Suárez-Benjumea, Alejandro
A1 Suñer-Poblet, Marta
A1 González-Corvillo, Carmen
A1 Martín-Gutiérrez, Guillermo
A1 Bernal, Gabriel
A1 Pachón, Jerónimo
A1 Pachón-Ibáñez, María Eugenia
A1 Cordero, Elisa
K1 asymptomatic bacteriuria
K1 cystitis
K1 kidney recipients
K1 prospective observational cohort
K1 urinary tract infections
AB This study aims to define the epidemiologic, clinical, and microbiological features of asymptomatic bacteriuria (AB) and cystitis in kidney transplantation recipients (KTRs), and to determine the impact of antimicrobial therapy of AB and the risk factors of cystitis. We conducted a prospective observational study of AB and cystitis in KTRs from January to June 2017. One-hundred ninety seven KTRs were included: 175 (88.8%) with AB and 22 (11.2%) with cystitis. The most frequent etiologies were Escherichia coli, Klebsiellapneumoniae, Enterococcusfaecalis, and Pseudomonas aeruginosa. No differences were observed regarding the etiologies, antimicrobial susceptibility patterns, and microbiologic outcomes in AB vs. cystitis. The treatment of AB diminished the microbiological cure and increased the rates of microbiologic relapses and reinfections; in addition, treated AB patients showed a trend of developing symptomatic urinary tract infection in the following six months. The analysis of the data identified the following independent risk factors for cystitis during the six months of follow-up: AB treatment, thymoglobulin induction, previous acute pyelonephritis, and time since transplantation
SN 2079-6382
YR 2021
FD 2021-02-22
LK https://hdl.handle.net/10668/27483
UL https://hdl.handle.net/10668/27483
LA en
DS RISalud
RD Apr 12, 2025