TY - JOUR AU - Arbulo-Echevarria, Mikel M AU - Narbona-Sanchez, Isaac AU - Fernandez-Ponce, Cecilia M AU - Vico-Barranco, Inmaculada AU - Rueda-Ygueravide, Mª Dolores AU - Dustin, Michael L AU - Miazek, Arkadiusz AU - Duran-Ruiz, Mª Carmen AU - Garcia-Cozar, Francisco AU - Aguado, Enrique PY - 2018 DO - 10.3389/fimmu.2018.00115 SN - 1664-3224 UR - http://hdl.handle.net/10668/12152 T2 - Frontiers in immunology AB - The adaptor protein linker for activation of T cells (LAT) has an essential role transducing activatory intracellular signals coming from the TCR/CD3 complex. Previous reports have shown that upon T-cell activation, LAT interacts with the tyrosine... LA - en PB - Frontiers Research Foundation KW - CD3 KW - LAT KW - Lck KW - TCR KW - Signaling KW - Adaptor proteins, signal transducing KW - Amino acids KW - Cell line KW - Humans KW - Lymphocyte specific protein tyrosine kinase p56(lck) KW - Membrane proteins KW - Receptors, antigen, T-cell KW - ZAP-70 protein-tyrosine kinase TI - A Stretch of Negatively Charged Amino Acids of Linker for Activation of T-Cell Adaptor Has a Dual Role in T-Cell Antigen Receptor Intracellular Signaling. TY - research article VL - 9 ER -