TY - JOUR AU - Yan, Qingqing AU - Wulfridge, Phillip AU - Doherty, John AU - Fernandez-Luna, Jose L AU - Real, Pedro J AU - Tang, Hsin-Yao AU - Sarma, Kavitha PY - 2022 DO - 10.1038/s41467-021-27722-6 UR - http://hdl.handle.net/10668/19536 T2 - Nature communications AB - R-loops are three-stranded nucleic acid structures that accumulate on chromatin in neurological diseases and cancers and contribute to genome instability. Using a proximity-dependent labeling system, we identified distinct classes of proteins that... LA - en KW - Animals KW - Cell Differentiation KW - Chromatin KW - Embryonic Stem Cells KW - Genomic Instability KW - HEK293 Cells KW - Homeodomain Proteins KW - Humans KW - Induced Pluripotent Stem Cells KW - Mice KW - Mutation KW - Nerve Tissue Proteins KW - Neurons KW - Proteomics KW - R-Loop Structures KW - RNA KW - Zinc Fingers TI - Proximity labeling identifies a repertoire of site-specific R-loop modulators. TY - research article VL - 13 ER -