RT Journal Article T1 Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk. A1 Papandreou, Christopher A1 Babio, Nancy A1 Diaz-Lopez, Andres A1 Martinez-Gonzalez, Miguel A A1 Becerra-Tomas, Nerea A1 Corella, Dolores A1 Schröder, Helmut A1 Romaguera, Dora A1 Vioque, Jesus A1 Alonso-Gomez, Angel M A1 Wärnberg, Julia A1 Martinez, Alfredo J A1 Serra-Majem, Lluís A1 Estruch, Ramon A1 Muñoz-Garach, Araceli A1 Lapetra, Jose A1 Pinto, Xavier A1 Tur, Josep A A1 Garcia-Rios, Antonio A1 Bueno-Cavanillas, Aurora A1 Delgado-Rodriguez, Miguel A1 Matia-Martin, Pilar A1 Daimiel, Lidia A1 M Sanchez, Vicente A1 Vidal, Josep A1 Vazquez, Clotilde A1 Ros, Emilio A1 Ruiz-Canela, Miguel A1 Bullo, Monica A1 Sorli, Jose V A1 Quifer, Mireia A1 Colom, Antoni A1 Oncina-Canovas, Alejandro A1 T Sierra, Lucas A1 Baron-Lopez, Javier A1 Perez-Farinos, Napoleon A1 Abete, Itziar A1 Sanchez-Villegas, Almudena A1 Casas, Rosa A1 F Garcia, Jose C A1 Santos-Lozano, Jose M A1 Corbella, Emili A1 Del M Bibiloni, Maria A1 Diez-Espino, Javier A1 Asensio, Eva M A1 Torras, Laura A1 Morey, Marga A1 Compañ-Gabucio, Laura A1 S Lete, Itziar A1 Cenoz-Osinaga, Juan C A1 Castañer, Olga A1 Salas-Salvado, Jordi K1 Actigraphy K1 Serum uric acid K1 Serum uric acid to creatinine ratio K1 Sleep duration AB The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations (β = 0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio (β = 0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio. PB MDPI YR 2019 FD 2019-03-29 LK http://hdl.handle.net/10668/13784 UL http://hdl.handle.net/10668/13784 LA en NO Papandreou C, Babio N, Díaz-López A, Martínez-González MÁ, Becerra-Tomas N, Corella D, et al. Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk. Nutrients. 2019 Apr 1;11(4):761 DS RISalud RD Apr 7, 2025