RT Journal Article
T1 Impact of SARS-CoV-2 positivity on clinical outcome among STEMI patients undergoing mechanical reperfusion: Insights from the ISACS STEMI COVID 19 registry.
A1 De Luca, Giuseppe
A1 Debel, Niels
A1 Cercek, Miha
A1 Jensen, Lisette Okkels
A1 Vavlukis, Marija
A1 Calmac, Lucian
A1 Johnson, Tom
A1 Ferrer, Gerard Rourai
A1 Ganyukov, Vladimir
A1 Wojakowski, Wojtek
A1 Kinnaird, Tim
A1 von Birgelen, Clemens
A1 Cottin, Yves
A1 IJsselmuiden, Alexander
A1 Tuccillo, Bernardo
A1 Versaci, Francesco
A1 Royaards, Kees-Jan
A1 Berg, Jurrien Ten
A1 Laine, Mika
A1 Dirksen, Maurits
A1 Siviglia, Massimo
A1 Casella, Gianni
A1 Kala, Petr
A1 Díez Gil, José Luis
A1 Banning, Adrian
A1 Becerra, Victor
A1 De Simone, Ciro
A1 Santucci, Andrea
A1 Carrillo, Xavier
A1 Scoccia, Alessandra
A1 Amoroso, Giovanni
A1 Van't Hof, Arnoud Wj
A1 Kovarnik, Tomas
A1 Tsigkas, Grigorios
A1 Mehilli, Julinda
A1 Gabrielli, Gabriele
A1 Rios, Xacobe Flores
A1 Bakraceski, Nikola
A1 Levesque, Sébastien
A1 Cirrincione, Giuseppe
A1 Guiducci, Vincenzo
A1 Kidawa, Michał
A1 Spedicato, Leonardo
A1 Marinucci, Lucia
A1 Ludman, Peter
A1 Zilio, Filippo
A1 Galasso, Gennaro
A1 Fabris, Enrico
A1 Menichelli, Maurizio
A1 Garcia-Touchard, Arturo
A1 Manzo, Stephane
A1 Caiazzo, Gianluca
A1 Moreu, Jose
A1 Forés, Juan Sanchis
A1 Donazzan, Luca
A1 Vignali, Luigi
A1 Teles, Rui
A1 Benit, Edouard
A1 Agostoni, Pierfrancesco
A1 Ojeda, Francisco Bosa
A1 Lehtola, Heidi
A1 Camacho-Freiere, Santiago
A1 Kraaijeveld, Adriaan
A1 Antti, Ylitalo
A1 Boccalatte, Marco
A1 Deharo, Pierre
A1 Martínez-Luengas, Iñigo Lozano
A1 Scheller, Bruno
A1 Varytimiadi, Efthymia
A1 Moreno, Raul
A1 Uccello, Giuseppe
A1 Faurie, Benjamin
A1 Gutierrez Barrios, Alejandro
A1 Milewski, Marek
A1 Bruwiere, Ewout
A1 Smits, Pieter
A1 Wilbert, Bor
A1 Di Uccio, Fortunato Scotto
A1 Parodi, Guido
A1 Kedhi, Elvin
A1 Verdoia, Monica
K1 SARS-CoV-2
K1 ST segment elevation myocardial infarction
K1 Thrombosis(please add them)
AB SARS-Cov-2 predisposes patients to thrombotic complications, due to excessive inflammation, endothelial dysfunction, platelet activation, and coagulation/fibrinolysis disturbances. The aim of the present study was to evaluate clinical characteristics and prognostic impact of SARS-CoV-2 positivity among STEMI patients undergoing primary percutaneous coronary intervention (PPCI). We selected SARS-CoV-2 positive patients included in the ISACS-STEMI COVID-19, a retrospective multicenter European registry including 6609 STEMI patients treated with PPCI from March 1st until April 30th, in 2019 and 2020. As a reference group, we randomly sampled 5 SARS-Cov-2 negative patients per each SARS-CoV-2 positive patient, individually matched for age, sex, and hospital/geographic area. Study endpoints were in-hospital mortality, definite stent thrombosis, heart failure. Our population is represented by 62 positive SARS-CoV-2 positive patients who were compared with a matched population of 310 STEMI patients. No significant difference was observed in baseline characteristics or the modality of access to the PCI center. In the SARS-CoV-2 positive patients, the culprit lesion was more often located in the RCA (p  Our study showed that among STEMI patients, SARS-CoV-2 positivity is associated with larger thrombus burden, a remarkably higher mortality but also higher rates of in-stent thrombosis and heart failure.
YR 2021
FD 2021-07-21
LK http://hdl.handle.net/10668/18377
UL http://hdl.handle.net/10668/18377
LA en
DS RISalud
RD Apr 5, 2025