TY - JOUR AU - Martinez-Gregorio, Hector AU - Rojas-Jimenez, Ernesto AU - Cesar Mejia-Gomez, Javier AU - Diaz-Velasquez, Clara AU - Quezada-Urban, Rosalia AU - Vallejo-Lecuona, Fernando AU - de la Cruz-Montoya, Aldo AU - Iris Porras-Reyes, Fany AU - Manuel Perez-Sanchez, Victor AU - Aquiles Maldonado-Martinez, Hector AU - Robles-Estrada, Maybelline AU - Bargallo-Rocha, Enrique AU - Cabrera-Galeana, Paula AU - Ramos-Ramirez, Maritza AU - Irasema Chirino, Yolanda AU - Alonso Herrera, Luis AU - Ignacio Terrazas, Luis AU - Frecha, Cecilia AU - Oliver, Javier AU - Perdomo, Sandra AU - Vaca-Paniagua, Felipe PY - 2021 DO - 10.3390/cancers13205091 UR - https://hdl.handle.net/10668/24574 T2 - Cancers AB - Simple Summary: Triple-negative breast cancer (TNBC) is a clinically, phenotypically, and molecularly heterogeneous disease. This heterogeneity is a factor that negatively impacts therapy response. To analyze evolutionary patterns and the genomic... LA - en PB - Mdpi KW - triple-negative breast cancer KW - tumor evolution KW - metastasis KW - lymph nodes KW - early divergence KW - targeted therapies KW - Genomic characterization KW - Signatures KW - Insights KW - Tumor KW - Landscape KW - History TI - The Evolution of Clinically Aggressive Triple-Negative Breast Cancer Shows a Large Mutational Diversity and Early Metastasis to Lymph Nodes TY - research article VL - 13 ER -