RT Journal Article
T1 Hepatotoxicity by Dietary Supplements: A Tabular Listing and Clinical Characteristics.
A1 García-Cortés, Miren
A1 Robles-Díaz, Mercedes
A1 Ortega-Alonso, Aida
A1 Medina-Caliz, Inmaculada
A1 Andrade, Raul J
K1 Herbalife products
K1 Hydroxycut
K1 Oxyelite Pro
K1 anabolic steroids
K1 dietary supplements
K1 green tea
K1 hepatotoxicity
K1 liver injury
K1 usnic acid
K1 vitamin A
AB Dietary supplements (DS) are extensively consumed worldwide despite unproven efficacy. The true incidence of DS-induced liver injury (DSILI) is unknown but is probably under-diagnosed due to the general belief of safety of these products. Reported cases of herbals and DS-induced liver injury are increasing worldwide. The aim of this manuscript is to report a tabular listing with a description of DS associated with hepatotoxicity as well as review the phenotype and severity of DSILI. Natural remedies related to hepatotoxicity can be divided into herbal product-induced liver injury and DS-induced liver injury. In this article, we describe different DS associated with liver injury, some of them manufactured DS containing several ingredients (Herbalife™ products, Hydroxycut™, LipoKinetix™, UCP-1 and OxyELITE™) while others have a single ingredient (green tea extract, linoleic acid, usnic acid, 1,3-Dimethylamylamine, vitamin A, Garcinia cambogia and ma huang). Additional DS containing some of the aforementioned ingredients implicated in liver injury are also covered. We have also included illicit androgenic anabolic steroids for bodybuilding in this work, as they are frequently sold under the denomination of DS despite being conventional drugs.
YR 2016
FD 2016-04-09
LK http://hdl.handle.net/10668/9989
UL http://hdl.handle.net/10668/9989
LA en
DS RISalud
RD Apr 19, 2025