TY  - JOUR
AU  - Simon, Iris
AU  - Perales, Sonia
AU  - Casado-Medina, Laura
AU  - Rodríguez-Martínez, Alba
AU  - Garrido-Navas, Maria del Carmen
AU  - Puche-Sanz, Ignacio
AU  - Diaz-Mochon, Juan J.
AU  - Alaminos, Clara
AU  - Lupiañez, Pablo
AU  - Lorente, Jose A.
AU  - Serrano, María J.
AU  - Real, Pedro J.
PY  - 2021
DO  - 10.3390/cancers13061483
UR  - http://hdl.handle.net/10668/4185
T2  - Cancers
AB  - Androgen deprivation therapy (ADT) and novel hormonal agents (NHAs) (Abiraterone and Enzalutamide) are the goal standard for metastatic prostate cancer (PCa) treatment. Although ADT is initially effective, a subsequent castration resistance status...
LA  - en
PB  - MDPI
KW  - Castration resistant prostate cancer
KW  - Androgen receptor
KW  - AR-V7
KW  - AR-V9
KW  - Transcriptional regulation
KW  - Novel hormonal agents
KW  - Abiraterone
KW  - Enzalutamide
KW  - Cross-resistance
KW  - Neoplasias de la próstata resistentes a la castración
KW  - Andrógenos
KW  - Elementos reguladores de la transcripción
KW  - Acetato de abiraterona
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Receptors, Cytoplasmic and Nuclear::Receptors, Steroid::Receptors, Androgen
KW  - Medical Subject Headings::Diseases::Male Urogenital Diseases::Urogenital Neoplasms::Genital Neoplasms, Male::Prostatic Neoplasms::Prostatic Neoplasms, Castration-Resistant
KW  - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormone Antagonists::Androgen Antagonists
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Androgens
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::RNA Processing, Post-Transcriptional::RNA Splicing::Alternative Splicing
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Cytophotometry::Flow Cytometry
KW  - Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Motivation::Goals
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Protein Isoforms
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Urogenital Surgical Procedures::Castration
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype
TI  - Cross-Resistance to Abiraterone and Enzalutamide in Castration Resistance Prostate Cancer Cellular Models Is Mediated by AR Transcriptional Reactivation
TY  - research article
ER  -