TY  - JOUR
AU  - Hartmann, Oliver
AU  - Reissland, Michaela
AU  - Maier, Carina R
AU  - Fischer, Thomas
AU  - Prieto-Garcia, Cristian
AU  - Baluapuri, Apoorva
AU  - Schwarz, Jessica
AU  - Schmitz, Werner
AU  - Garrido-Rodriguez, Martin
AU  - Pahor, Nikolett
AU  - Davies, Clare C
AU  - Bassermann, Florian
AU  - Orian, Amir
AU  - Wolf, Elmar
AU  - Schulze, Almut
AU  - Calzado, Marco A
AU  - Rosenfeldt, Mathias T
AU  - Diefenbacher, Markus E
PY  - 2021
DO  - 10.3389/fcell.2021.641618
SN  - 2296-634X
UR  - http://hdl.handle.net/10668/17366
T2  - Frontiers in cell and developmental biology
AB  - Lung cancer is the most common cancer worldwide and the leading cause of cancer-related deaths in both men and women. Despite the development of novel therapeutic interventions, the 5-year survival rate for non-small cell lung cancer (NSCLC) patients...
LA  - en
PB  - Frontiers Research Foundation
KW  - CRISPR-Cas9
KW  - JUN
KW  - KRAS
KW  - MYC
KW  - TP53
KW  - Lung cancer
KW  - Mouse model
KW  - Non-small cell lung cancer
KW  - Carcinoma, non-small-cell lung
KW  - Lung neoplasms
KW  - Gene editing
KW  - Point mutation
KW  - Translational research, biomedical
KW  - Gene deletion
KW  - Epithelial cells
KW  - Gene targeting
TI  - Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease.
TY  - research article
VL  - 9
ER  -