TY - JOUR AU - Gonzalez Del Alba, A AU - Mendez-Vidal, M J AU - Vazquez, S AU - Castro, E AU - Climent, M A AU - Gallardo, E AU - Gonzalez-Billalabeitia, E AU - Lorente, D AU - Maroto, J P AU - Arranz, J A PY - 2021 DO - 10.1007/s12094-021-02561-5 UR - http://hdl.handle.net/10668/17228 T2 - Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico AB - The treatment of advanced prostate cancer has evolved due to recent advances in molecular research and new drug development. Dynamic aberrations in the androgen receptor, DNA repair genes, PTEN-PI3K, and other pathways drive the behavior of advanced... LA - en KW - Androgen KW - Biomarkers KW - Castration KW - Molecular KW - Research KW - Androgen antagonists KW - Androstenes KW - Antineoplastic agents KW - Benzamides KW - Combined modality therapy KW - Docetaxel KW - Genes, BRCA1 KW - Genes, BRCA2 KW - Genetic testing KW - Humans KW - Male KW - Medical oncology KW - Nitriles KW - Orchiectomy KW - Phenylthiohydantoin KW - Phthalazines KW - Piperazines KW - Prostatic neoplasms KW - Prostatic neoplasms, castration-resistant KW - Radiotherapy KW - Randomized controlled trials as topic KW - Societies, medical KW - Spain KW - Thiohydantoins TI - SEOM clinical guidelines for the treatment of advanced prostate cancer (2020). TY - research article VL - 23 ER -