RT Journal Article
T1 Exercise Intolerance in Post-Acute Sequelae of COVID-19 and the Value of Cardiopulmonary Exercise Testing- a Mini-Review.
A1 Aparisi, Álvaro
A1 Ladrón, Raquel
A1 Ybarra-Falcón, Cristina
A1 Tobar, Javier
A1 San Román, J Alberto
K1 autonomic dysfunction
K1 cardiopulmonary exercise testing
K1 exercise intolerance
K1 hyperventilation
K1 post-acute sequelae COVID-19
AB Coronavirus disease (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with systemic organ damage in the most severe forms. Long-term complications of SARS-CoV-2 appear to be restricted to severe presentations of COVID-19, but many patients with persistent symptoms have never been hospitalized. Post-acute sequelae of COVID-19 (PASC) represents a heterogeneous group of symptoms characterized by cardiovascular, general, respiratory, and neuropsychiatric sequelae. The pace of evidence acquisition with PASC has been rapid, but the mechanisms behind it are complex and not yet fully understood. In particular, exercise intolerance shares some features with other classic respiratory and cardiac disorders. However, cardiopulmonary exercise testing (CPET) provides a comprehensive assessment and can unmask the pathophysiological mechanism behind exercise intolerance in gray-zone PASC. This mini-review explores the utility of CPET and aims to provide a comprehensive assessment of PASC by summarizing the current evidence.
SN 2296-858X
YR 2022
FD 2022-07-22
LK http://hdl.handle.net/10668/20606
UL http://hdl.handle.net/10668/20606
LA en
DS RISalud
RD Apr 6, 2025