RT Journal Article
T1 Intestinal colonization due to Escherichia coli ST131: risk factors and prevalence.
A1 Morales-Barroso, Isabel
A1 Lopez-Cerero, Lorena
A1 Navarro, Maria Dolores
A1 Gutierrez-Gutierrez, Belen
A1 Pascual, Alvaro
A1 Rodriguez-Baño, Jesus
K1 Carriage
K1 Escherichia coli
K1 Intestinal colonisation
K1 Outcome
K1 Prevalence colonization
K1 Risk factors
K1 ST131
AB Escherichia coli sequence type 131 (ST131) is a successful clonal group that has dramatically spread during the last decades and is considered an important driver for the rapid increase of quinolone resistance in E. coli. Risk factors for rectal colonization by ST131 Escherichia coli (irrespective of ESBL production) were investigated in 64 household members (18 were colonized) and 54 hospital contacts (HC; 10 colonized) of 34 and 30 index patients with community and nosocomial infection due to these organisms, respectively, using multilevel analysis with a p limit of  Colonization among household members was associated with the use of proton-pump inhibitors (PPI) by the household member (OR = 3.08; 95% CI: 0.88-10.8) and higher age of index patients (OR = 1.05; 95% CI; 1.01-1.10), and among HC, with being bed-ridden (OR = 21.1; 95% CI: 3.61-160.0) and having a urinary catheter (OR = 8.4; 95% CI: 0.87-76.9). Use of PPI and variables associated with higher need of person-to-person contact are associated with increased risk of rectal colonization by ST131. These results should be considered for infection control purposes.
PB BioMed Central Ltd.
YR 2018
FD 2018-11-15
LK http://hdl.handle.net/10668/13231
UL http://hdl.handle.net/10668/13231
LA en
NO Morales Barroso I, López-Cerero L, Navarro MD, Gutiérrez-Gutiérrez B, Pascual A, Rodríguez-Baño J. Intestinal colonization due to Escherichia coli ST131: risk factors and prevalence. Antimicrob Resist Infect Control. 2018 Nov 15;7:135.
DS RISalud
RD Sep 5, 2025