RT Journal Article
T1 Predictors of Global Non-Motor Symptoms Burden Progression in Parkinson's Disease. Results from the COPPADIS Cohort at 2-Year Follow-Up.
A1 Santos-García, Diego
A1 de Deus, Teresa
A1 Cores, Carlos
A1 Canfield, Hector
A1 Paz González, Jose M
A1 Martínez Miró, Cristina
A1 Valdés Aymerich, Lorena
A1 Suárez, Ester
A1 Jesús, Silvia
A1 Aguilar, Miquel
A1 Pastor, Pau
A1 Planellas, Lluis
A1 Cosgaya, Marina
A1 García Caldentey, Juan
A1 Caballol, Nuria
A1 Legarda, Ines
A1 Hernández-Vara, Jorge
A1 Cabo, Iria
A1 López Manzanares, Lydia
A1 González Aramburu, Isabel
A1 Ávila Rivera, Maria A
A1 Catalán, Maria J
A1 Nogueira, Victor
A1 Puente, Victor
A1 Dotor, Julio
A1 Borrué, Carmen
A1 Solano, Berta
A1 Álvarez Sauco, Maria
A1 Vela, Lydia
A1 Escalante, Sonia
A1 Cubo, Esther
A1 Carrillo, Francisco
A1 Martínez Castrillo, Juan C
A1 Sánchez Alonso, Pilar
A1 Alonso, Gemma
A1 López Ariztegui, Nuria
A1 Gastón, Itziar
A1 Kulisevsky, Jaime
A1 Blázquez, Marta
A1 Seijo, Manuel
A1 Rúiz Martínez, Javier
A1 Valero, Caridad
A1 Kurtis, Monica
A1 de Fábregues, Oriol
A1 Ardura, Jessica
A1 Alonso, Ruben
A1 Ordás, Carlos
A1 López Díaz, Luis M
A1 McAfee, Darrian
A1 Martinez-Martin, Pablo
A1 Mir, Pablo
A1 Coppadis Study Group, 
K1 Parkinson’s disease
K1 mood
K1 non-motor symptoms
K1 progression
K1 quality of life
AB Background and Objective: Non-motor symptoms (NMS) progress in different ways between Parkinson's disease (PD) patients. The aim of the present study was to (1) analyze the change in global NMS burden in a PD cohort after a 2-year follow-up, (2) to compare the changes with a control group, and (3) to identify predictors of global NMS burden progression in the PD group. Material and Methods: PD patients and controls, recruited from 35 centers of Spain from the COPPADIS cohort from January 2016 to November 2017, were followed-up with after 2 years. The Non-Motor Symptoms Scale (NMSS) was administered at baseline (V0) and at 24 months ± 1 month (V2). Linear regression models were used for determining predictive factors of global NMS burden progression (NMSS total score change from V0 to V2 as dependent variable). Results: After the 2-year follow-up, the mean NMS burden (NMSS total score) significantly increased in PD patients by 18.8% (from 45.08 ± 37.62 to 53.55 ± 42.28; p
SN 2075-4426
YR 2021
FD 2021-06-30
LK https://hdl.handle.net/10668/27682
UL https://hdl.handle.net/10668/27682
LA en
DS RISalud
RD Apr 4, 2025