RT Journal Article T1 Consensus document of the Spanish Association for Study of the Liver on the treatment of hepatitis B virus infection (2020). T2 Documento de consenso de la Asociación Española para el Estudio del Hígado sobre el tratamiento de la infección por el virus de la hepatitis B (2020). A1 Rodríguez, Manuel A1 Buti, María A1 Esteban, Rafael A1 Lens, Sabela A1 Prieto, Martín A1 Suárez, Emilio A1 García-Samaniego, Javier K1 ADN-VHB K1 AEEH document K1 Documento de la AEEH K1 Entecavir K1 HBV-DNA K1 HBsAg K1 Hepatitis B K1 Hepatocarcinoma K1 Hepatocellular carcinoma K1 Interferon K1 Interferón K1 Tenofovir K1 Tenofovir alafenamida K1 Tenofovir alafenamide AB Hepatitis B virus (HBV) infection remains a global public health problem. HBV vaccination is the most effective tool to reduce the incidence of HBV disease. Despite there has not been new clinical developments for the treatment of chronic hepatitis B in the last few years, changing epidemiology and current insights on natural history, diagnostic tools and therapy indications make necessary an update of the former version of the consensus document of the Spanish Association for Study of the Liver on the treatment of hepatitis B infection published in 2012. The current document updates the management of chronic hepatitis B. The treatment of choice is the long-term administration of a nucleos(t)ide analogue with high barrier to resistance (entecavir, tenofovir or tenofovir alafenamide). Pegylated interferon may be an option in patients with non-advanced liver disease, but its applicability is limited due to the low efficacy and poor tolerability. All patients must be monitored for the risk of progression to advanced liver disease and development of hepatocellular carcinoma. SN 0210-5705 YR 2020 FD 2020-08-07 LK http://hdl.handle.net/10668/16084 UL http://hdl.handle.net/10668/16084 LA en LA es DS RISalud RD Feb 18, 2025