TY  - JOUR
AU  - Martín-Montañez, Elisa
AU  - Valverde, Nadia
AU  - Ladrón de Guevara-Miranda, David
AU  - Lara, Estrella
AU  - Romero-Zerbo, Yanina S.
AU  - Millon, Carmelo
AU  - Boraldi, Federica
AU  - Ávila-Gámiz, Fabiola
AU  - Pérez-Cano, Ana M.
AU  - Garrido-Gil, Pablo
AU  - Labandeira-Garcia, Jose Luis
AU  - Santin, Luis J.
AU  - Pavia, Jose
AU  - Garcia-Fernandez, Maria
PY  - 2021
DO  - 10.1016/j.redox.2021.102095
UR  - http://hdl.handle.net/10668/4269
T2  - Redox Biology
AB  - Oxidative distress and mitochondrial dysfunction, are key factors involved in the pathophysiology of Parkinson's disease (PD). The pleiotropic hormone insulin-like growth factor II (IGF-II) has shown neuroprotective and antioxidant effects in some...
LA  - en
PB  - Elsevier B.V.
KW  - Insulin like growth factor-II
KW  - Neuroprotection
KW  - Mitochondria
KW  - Oxidative distress
KW  - Parkinson’s disease
KW  - 1-methyl-4-phenylpyridinium
KW  - Dopaminergic neurons
KW  - Factor II del crecimiento similar a la insulina
KW  - Neuroprotección
KW  - Mitocondrias
KW  - Estrés oxidativo
KW  - Enfermedad de Parkinson
KW  - 1-metil-4-fenilpiridinio
KW  - Neuronas dopaminérgicas
KW  - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Pyridines::Pyridinium Compounds::1-Methyl-4-phenylpyridinium
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Anatomy::Nervous System::Neurons::Dopaminergic Neurons
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Somatomedins::Insulin-Like Growth Factor II
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress
KW  - Medical Subject Headings::Diseases::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Basal Ganglia Diseases::Parkinsonian Disorders::Parkinson Disease
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Protective Agents::Neuroprotective Agents
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Basic-Leucine Zipper Transcription Factors::NF-E2-Related Factor 2
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Antioxidants
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Peptide::Receptors, Growth Factor::Receptors, Somatomedin::Receptor, IGF Type 2
KW  - Medical Subject Headings::Diseases::Nervous System Diseases::Neurodegenerative Diseases
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Up-Regulation
KW  - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases::TOR Serine-Threonine Kinases
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Cell Culture Techniques
KW  - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones
TI  - Insulin-like growth factor II prevents oxidative and neuronal damage in cellular and mice models of Parkinson's disease
TY  - research article
ER  -